基本信息

姓名：张弋峰

职务、职称、社会兼职：

张弋峰，男，1993年8月，博士研究生，副教授（校聘），硕士生导师。2024年9月以公派访问学者身份赴美国天普大学Lewis Katz医学院进修1年。江西中医药大学江西省中药防治血管重塑相关疾病重点实验室科研骨干，主讲课程《生物化学》。主要从事中药或天然产物改善内皮功能障碍防治心血管相关疾病的药理研究以及基于多组学整合的生物信息学方法系统鉴别心血管疾病的潜在发病机制及中药干预的分子作用靶点。近五年来在Nature、Atherosclerosis、Science China Life sciences, Meat science, Food & Function 等杂志发表SCI论文18篇，主持江西省自然科学基金青年项目和面上项目各1项，江西省教育厅科学技术研究一般项目1项、江西省中医药管理局科技计划课题1项，参与国家自然科学基金地区项目2项，横向课题1项目。担任中国中医药信息学会和方药量效研究分会理事。

招生专业及研究方向

招生层次：硕士

招生专业：中西医结合基础

研究方向：中药及天然产物防治心血管相关疾病作用机制研究；大数据挖掘：多源组学数据联合的生物信息学研究。

论文发表：

1） 第一作者和通讯作者：

（1） Chu S, Shan D, He L, Yang S, Feng Y, Zhang Y*, Yu J*. Anemoside B4 attenuates abdominal aortic aneurysm by limiting smooth muscle cell transdifferentiation and its mediated inflammation. Front Immunol. 2024 May 31;15:1412022. doi: 10.3389/fimmu.2024.1412022. PMID: 38881898; PMCID: PMC11176519.

（2） He L, Palos-Jasso A, Yi Y, Qin M, Qiu L, Yang X, Zhang Y*, Yu J. Bioinformatic Analysis Revealed the Essential Regulatory Genes and Pathways of Early and Advanced Atherosclerotic Plaque in Humans. Cells. 2022 Dec 8;11(24):3976. doi: 10.3390/cells11243976. PMID: 36552740; PMCID: PMC9776921.

（3） Zhang Y, Sun Y, Wu Z, Xiong X, Zhang J, Ma J, Xiao S, Huang L, Yang B. Subcutaneous and intramuscular fat transcriptomes show large differences in network organization and associations with adipose traits in pigs. Sci China Life Sci. 2021 Oct;64(10):1732-1746. doi: 10.1007/s11427-020-1824-7. Epub 2021 Jan 27. PMID: 33527326.

（4） Yifeng Zhang, Junjie Zhang .et al, Lusheng Huang* Bin Yang*. Genetic correlation of fatty acid composition with growth, carcass, fat deposition and meat quality traits based on GWAS data in six pig populations. Meat science, 2019, 150: 47-55. (IF: 3.64, 一区)

（5） Junjie Zhang^#, Yifeng Zhang^#, Huanfa Gong, Leilei Cui, Tao Huang, Huashui Ai, Jun Ren, Lusheng Huang^*, Bin Yang^*. Genetic mapping using 1.4M SNP array refined loci for fatty acid composition traits in Chinese Erhualian and Bamaxiang pigs. J Anim Breed Genet 2017, 134(6):472-483.（IF：1.88, 二区）

2） 其他排序

（1） Zhao S, Guo H, Qiu L, Zhong C, Xue J, Qin M, Zhang Y, Xu C, Xie Y, Yu J. Saponins from Allii Macrostemonis Bulbus attenuate atherosclerosis by inhibiting macrophage foam cell formation and inflammation. Sci Rep. 2024 Jun 5;14(1):12917. doi: 10.1038/s41598-024-61209-w. PMID: 38839811; PMCID: PMC11153636.

（2） Liu L, Qiu L, Xue J, Zhong C, Qin M, Zhang Y, Xu C, Xie Y, Yu J. Saponins from Allium macrostemon Bulbs Attenuate Endothelial Inflammation and Acute Lung Injury via the NF-κB/VCAM-1 Pathway. Molecules. 2024 Mar 11;29(6):1239. doi: 10.3390/molecules29061239. PMID: 38542876; PMCID: PMC10976117.

（3） Yang J, Cui L, Zhang Y, Ling Z, Zhang Z, Huang Y, Ma J, Xiao S, Yang B, Huang L. Unravelling the genetic basis for skeletal muscle mitochondrial DNA copy number variations in pigs. Sci China Life Sci. 2024 Jan;67(1):211-214. doi: 10.1007/s11427-022-2397-1. Epub 2023 Oct 25. PMID: 37906412.

（4） Yang H, Wu J, Huang X, Zhou Y, Zhang Y, Liu M, Liu Q, Ke S, He M, Fu H, Fang S, Xiong X, Jiang H, Chen Z, Wu Z, Gong H, Tong X, Huang Y, Ma J, Gao J, Charlier C, Coppieters W, Shagam L, Zhang Z, Ai H, Yang B, Georges M, Chen C, Huang L. ABO genotype alters the gut microbiota by regulating GalNAc levels in pigs. Nature. 2022 Jun;606(7913):358-367. doi: 10.1038/s41586-022-04769-z. Epub 2022 Apr 27. PMID: 35477154; PMCID: PMC9157047.

（5） Tang J, Qin M, Tang L, Shan D, Zhang C, Zhang Y, Wei H, Qiu L, Yu J. Enterobacter aerogenes ZDY01 inhibits choline-induced atherosclerosis through CDCA-FXR-FGF15 axis. Food Funct. 2021 Oct 19;12(20):9932-9946. doi: 10.1039/d1fo02021h. Erratum in: Food Funct. 2022 Jan 4;13(1):459. doi: 10.1039/d1fo90118d. PMID: 34492674.

（6） Junjie Zhang, Yifeng Zhang, Huanfa Gong .et al, Lusheng Huang* and Bin Yang* Landscape of Loci and Candidate Genes for Muscle Fatty Acid Composition in Pigs Revealed by Multiple Population Association Analysis[J]. Frontiers in genetics. 2019. 10(1067).

（7） Zhang, Q., Li, J., Huang, T., Zhang, Y., Xu, W., Huang, L., ... & Yang, B. Impacts of Mycoplasma loads and lung lesions on immune and hematological statuses of pigs in an eight-breed cross heterogeneous population[J]. Journal of Animal Science, 2020, 98(8): skaa235.

（8） Huang, Y., Zhou, L., Zhang, J., Liu, X., Zhang, Y., Cai, L., ... & Xiao, S. A large-scale comparison of meat quality and intramuscular fatty acid composition among three Chinese indigenous pig breeds[J]. Meat Science, 2020: 108182.

（9） Jiuxiu Ji, Lisheng Zhou, Yizhong Huang, Min Zheng, Xianxian Liu, Yifeng Zhang, Cong Huang, Song Peng, Qingjie Zeng, Liepeng Zhong, Bin Yang, Wanbo Li, Shijun Xiao, Junwu Ma⁎ and Lusheng Huang⁎ A whole-genome sequence-based association study on pork eating quality traits and cooking loss in a specially designed heterogeneous F6 pig population[J]. Meat science, 2018, 146: 160-167.

（10） X. Huang, T. Huang, W. Deng, G. Yan, H. Qiu, Y. Huang, S. Ke, Y. Hou, Y. Zhang, Z. Zhang, S. Fang, L. Zhou, B. Yang, J. Ren, H. Ai and L. Huang. Genome-wide association studies identify susceptibility loci affecting respiratory disease in Chinese Erhualian pigs under natural conditions[J]. Animal genetics, 2017, 48(1): 30-37.

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