许传铭，男，1988年5月生，副教授，博士生导师。中山大学药理学博士研究生(2013-2016)，美国犹他大学博士后(2016-2020)，入选江西省“双千计划”创新领军人才。主讲本科生《生理学》课程。近5年主持承担国家自然科学基金项目2项、江西省自然科学基金项目2项、江西省教育厅科技项目2项、江西省卫健委科技项目1项和美国心脏协会博士后基金1项。在《Hypertension》《J Am Soc Nephrol》《Proc Natl Acad Sci USA》《Acta Physiol》《J Hypertens》《FASEB J》等国际专业期刊共发表SCI论文30余篇。获美国心脏协会Hypertension New Investigator Travel Award（2020）、Kidney Council New Investigator Travel Award（2019）和Onsite Trainee Poster Award（2018）等奖项。兼任Journal of Exploratory Research in Pharmacology、Exploratory Research and Hypothesis in Medicine和Experimental and Therapeutic Medicine期刊编委及《现代医药卫生》和《新医学》青年编委。
研究方向/领域：
1. 组织局部肾素-血管紧张素-醛固酮系统在心血管疾病中的作用；
2. 中药及天然产物抗心血管疾病的作用机制研究；
研究生招生层次及专业：
1. 硕士研究生: 中西医结合基础（学术型）
2. 博士研究生：中药学（中药药性与配伍机制研究）（学术型）
代表性论著（*通讯作者）：
1. Xu C*, Yi X, Tang L, Wang H, Chu S, Yu J. Differential Regulation of Autophagy on Urine-Concentrating Capability through Modulating the Renal AQP2 Expression and Renin-Angiotensin System in Mice. American Journal of Physiology - Renal Physiology, 2023 Oct 1; 325(4):F503-F518.
2. Xu C*, Yi X, Qin M, Chu S, Liu C, Xiong J, Ouyang X, Yu J. PGE2 Stimulates Aldosterone Release via cAMP/sPRR/β-catenin Pathway in Mouse Inner Medullary Collecting Duct Cells. J Steroid Biochem Mol Biol. 2023 Jan; 225: 106205.
3. Xu C, Chen Y, Ramkumar N, Zou C, Sigmund CD, Yang T*. Collecting duct Renin Regulates Potassium Homeostasis in Mice. Acta Physiol (Oxf). 2023 Jan; 237(1): e13899.
4. Xu C, Yang G, Fu Z, Chen Y, Xie S, Wang F, Yang T*. Na+-Retaining Action of COX-2 (Cyclooxygenase-2) / EP1 Pathway in the Collecting Duct via Activation of Intrarenal Renin-Angiotensin-Aldosterone System and Epithelial Sodium Channel. Hypertension. 2022 Jun; 79(6):1190-1202.
5. Xu C, Chen Y, Wang F, Xie S, Yang T*. Soluble (Pro)Renin Receptor as a Negative Regulator of NCC (Na+-Cl− cotransporter) Activity. Hypertension. 2021 Sep; 78(4):1027-1038.
6. Xu C, Wang F, Chen Y, Xie S, Sng D, Reversade B, Yang T*. Elabela Antagonizes Intrarenal Renin-Angiotensin System to Lower Blood Pressure and Protects Against Renal Injury. Am J Physiol Renal Physiol. 2020 May 1; 318(5): F1122-F1135.
7. Xu C, Lu A, Lu X, Zhang L, Fang H, Zhou L, Yang T*. Activation of Renal (Pro)Renin Receptor Contributes to High Fructose-Induced Salt Sensitivity. Hypertension, 2017, 69(2):339-348.
8. Xu C, Fang H, Zhou L, Lu A, Yang T*. High potassium promotes mutual interaction between (pro)renin receptor and the local renin-angiotensin-aldosterone system in rat inner medullary collecting duct cells. Am J Physiol Cell Physiol. 2016 Oct 1; 311(4): C686-C695.
9. Xu C, Lu A, Wang H, Fang H, Zhou L, Sun P, Yang T*. (Pro)Renin Receptor Regulates Potassium Homeostasis through a Local Mechanism. Am J Physiol Renal Physiol. 2017 Sep 1; 313(3): F641-F656.
10. Xu C*. Extra-adrenal Aldosterone: a Mini Review Focusing on the Physiology and Pathophysiology of Intrarenal Aldosterone. Endocrine. 2024 Feb;83(2):285-301
11. Xu C*. Cardiovascular Aspects of ELABELA: a Potential Diagnostic Biomarker and Therapeutic Target. Vascular Pharmacology. 2023, 151: 107193.
12. Xu C*, Liu C#, Xiong J#, Yu J. Cardiovascular Aspects of the (Pro)Renin Receptor: Function and Significance. FASEB J. 2022 Apr; 36(4): e22237.
13. Xu C*, Yu J. Pathophysiological Mechanisms of Hypertension Development Induced by Fructose Consumption. Food & Function, 2022 Feb 21; 13: 1702-1717.
14. Chen Y, Xu C*. The Interaction Partners of (Pro)Renin Receptor in the Distal Nephron. FASEB J. 2020 Nov; 34(11):14136-14149.
15. Xu C*. The Elabela in hypertension, cardiovascular disease, renal disease, and preeclampsia: an update. J Hypertens. 2021. 39: 12-22.
招生邮箱：xuchuanming2008@163.com
